Efficacy of ciprofloxacin and moxifloxacin against Nocardia brasiliensis in vitro and in an experimental model of actinomycetoma in BALB/c mice.

نویسندگان

  • Brenda Edith Chacon-Moreno
  • Oliverio Welsh
  • Norma Cavazos-Rocha
  • Maria de la Luz Salazar-Cavazos
  • Hector Gerardo Garza-Lozano
  • Salvador Said-Fernandez
  • Jorge Ocampo-Candiani
  • Lucio Vera-Cabrera
چکیده

The efficacy of ciprofloxacin and moxifloxacin against Nocardia brasiliensis was evaluated by applying 25 mg of each drug/kg subcutaneously every 8 h in BALB/c mice infected with N. brasiliensis. A statistically significant difference was observed only with moxifloxacin. A moxifloxacin-trimethoprim-sulfamethoxazole combination was as active as when each compound was used alone.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 1  شماره 

صفحات  -

تاریخ انتشار 2009